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Immediate-release IR tablets: 250 to 1000 mg orally per day; amounts over 250 mg should be administered in divided doses Maintenance: Adjust doses individually based on symptomatology and ocular tension; for patients inadequately controlled on ER capsules 1 g/day, may supplement with IR tablets Doses in excess of 1 g/24 hours generally do not produce increased effects Various regimens have been used including: 250 mg orally every 4 alternatives to acetazolamide 250 mg orally twice a alternative to acetazolamide OR 500 mg orally followed by 125 mg or 250 mg orally every 4 hours In acute cases, IV therapy at same oral dosage has been used for rapid relief of ocular tension.

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