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Immediate-release IR tablets: 250 to 1000 mg orally per day; amounts over 250 mg should be administered in divided doses Maintenance: Adjust doses individually based on symptomatology and ocular tension; for patients inadequately controlled on ER capsules 1 g/day, may supplement with IR tablets Doses in excess of 1 g/24 hours generally do not produce increased effects Various regimens have been used including: 250 mg orally every 4 alternatives to acetazolamide 250 mg orally twice a alternative to acetazolamide OR 500 mg orally followed by 125 mg or 250 mg orally every 4 hours In acute cases, IV therapy at same oral dosage has been used for rapid relief of ocular tension.

A complementary effect has been observed alternative to acetazolamide used in conjunction with miotics or mydriatics.In rare cases, the inhibition of carbonic anhydrase may be strong enough to cause metabolic acidosis of clinical importance.

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The Acetazolamide structure is not an arylamine as there is no 6 alternative to acetazolamide benzene ring attached to a nitrogen or amino group.It also is not recommended for pregnant women or individuals with sulfonamide allergies and is known to interact with high-dose aspirin, cardiac glycosides, blood pressure medications, and lithium.

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