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For example, a 50% reduction of the maximum effect after single oral doses of 20, 50, and 100 mg occurred at 3. 5, and 6.ost arrhythmias are considered harmless and are left untreated.

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Other reported clinical experience in hypertensive patients has not identified differences in responses between elderly and younger patients. Of the 1, 90 patients with heart failure randomized to Metoprolol Succinate extended-release in the MERIT-HF trial.rg, "Mayo Clinic Healthy Living, and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

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