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Propranolol
Clinical data
Pronunciationprəʊˈpranəlɒl
Trade namesInderal, others
AHFS/Drugs.comMonograph
License dataEU  EMA:  by INN, US   FDA: Propranolol
Pregnancy categoryAU: C US: C (Risk not ruled out)
Routes of administrationBy mouth, rectal, intravenous
ATC codeC07AA05 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability26%
Protein binding90%
MetabolismLiver (extensive) 1A2, 2D6; minor: 2C19, 3A4
MetabolitesN-desisopropylpropranolol, 4’-hydroxypropanolol
Elimination half-life4–5 hours
ExcretionKidney (<1%)

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