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Clinical data
Trade namesLevitra, Staxyn, Vivanza
License dataEU  EMA:  by INN
Pregnancy categoryAU: B3 US: B (No risk in non-human studies)
Routes of administrationOral
ATC codeG04BE09 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding95%
MetabolismHepatic (CYP3A4)
Elimination half-life4–5 hours

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CYP3A4 Inhibitors: The dosage of LEVITRA may require adjustment in patients receiving potent CYP3A4 levitra mechanisms of action such as ketoconazole, itraconazole, ritonavir, indinavir, saquinavir, atazanavir, and clarithromycin as well as in other patients receiving moderate CYP3A4 inhibitors such as erythromycin see Drug Interactions 7.However, due to stock shortages and other unknown variables we cannot provide any guarantee.

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If you suffer from phenylketonuria a rare, hereditary disorder of the metabolism Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist Take a Vardenafil tablet about 25 to 60 minutes before sexual activity.White male, 104kg. No medical problem.

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8, 9, and 10 The pharmacokinetics of vardenafil are approximately dose proportional over the recommended dose range. Vardenafil is eliminated predominantly by hepatic metabolism, mainly by CYP3A4 and to a minor extent, CYP2C isoforms.

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Two patients on vardenafil in the trial reported episodes of transient cyanopsia objects appear blue Vardenafil is rapidly absorbed with absolute bioavailability of approximately 15% Maximum observed levitra mechanism of action concentrations after a single 20 mg dose in healthy volunteers are usually reached between 30 minutes and 2 hours median 60 minutes after oral dosing in the fasted state.

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Vardenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.These events, which may be accompanied by vardenafil therapy with STAXYN.

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